Dear Donn, Please do some research on line and you will Tell your wife to keep her leg elevated as much as possible when she is sitting. Even if she is eating at the table keep it elevated, this will help circulation. Keep a heating pad on low to med heat over the wound after it has been dressed. Do this several times a day. This will also keep the circulation of blood to the area to enhance healing. I have read research articles from university of maryland and NIH that there are two amino acids that need to be supplemented. The two are L glutamine and arginine. You can purchase them on line from vitamin shop or go to a natural food market. There are 20 amino acids found in protein such as meat, fish, chicken, turkey but these two are depleted when you are stressed and these two help the tissues to heal!!!! So even if she is eating lots of protein it may be helpful to supplement these two. Vitamin C supplements also help.
Severe acne usually indicates the necessity of prescription medication to treat the pimples. Prescription medications used to treat acne and pimples include isotretinoin , which is a retinoid . Historically, antibiotics such as tetracyclines and erythromycin were prescribed. While they were more effective than topical applications of benzoyl peroxide, the bacteria eventually grew resistant to the antibiotics and the treatments became less and less effective. Also, antibiotics had more side effects than topical applications, such as stomach cramps and severe discoloration of teeth. Common antibiotics prescribed by dermatologists include doxycycline and minocycline.  For more severe cases of acne dermatologists might recommend accutane , a retinoid that is the most potent of acne treatments. However, accutane can cause various side effects including vomiting, diarrhea, and birth defects if taken during pregnancy.