We guarantee our supplements to be the freshest and purest: Our powders and capsules contain only pure active ingredient with absolutely no additives. Other manufacturers, in an effort to keep costs down, dilute their products with cheap fillers and add chemical excipients to their products to speed up their manufacturing output. These practices cheat you out of the active ingredient. At NutraBio, we've perfected our manufacturing technology so that excipients aren't needed, that means no microcrystalline cellulose, magnesium stearate, silica or other fillers, just 100% pure active ingredient. NutraBio supplements are manufactured under the strictest standards producing the highest quality and purest supplements available anywhere. Our raw ingredients undergo state of the art HPLC analysis to insure zero tolerance for impurities and we manufacture our products every 2 weeks.
The structure of cyclocreatine is fairly flat (planar), which aids in passive diffusion across membranes. It has been used with success in an animal study, where mice suffered from a SLC6A8 (creatine transporter at the blood brain barrier) deficiency, which is not responsive to standard creatine supplementation.  This study failed to report increases in creatine stores in the brain, but noted a reduction of mental retardation associated with increased cyclocreatine and phosphorylated cyclocreatine storages.  As demonstrated by this animal study and previous ones, cyclocreatine is bioactive after oral ingestion   and may merely be a creatine mimetic, able to phosphorylate ADP via the creatine kinase system.