So I increased my use of make-up, got extra layers in my hair, avoided contact lenses so my glasses could frame my face, felt silly getting dressed up feeling like I shouldn’t have bothered, avoided guys so I didn’t fall into the f***boy trap when I was feeling low, admired how my more confident friends could just expect guys to like them and only took selfies with filters. When one random classmate once told me how beautiful he thought I was, I nearly cried. Then I got angry with myself for how grateful I was to hear that from a random classmate, when it should be me telling myself that. I also had to deal with being unable to fit into some clothes and losing what little muscle mass I had.
a) A wide range of psychiatric reactions including affective disorders (such as irritable, euphoric, depressed and labile mood and suicidal thoughts), psychotic reactions (including mania, delusions, hallucinations and aggravation of schizophrenia), behavioural disturbances, irritability, anxiety, sleep disturbances, and cognitive dysfunction including confusion and amnesia have been reported. Reactions are common and may occur in both adults and children. In adults, the frequency of severe reactions has been estimated to be 5-6%. Psychological effects have been reported on withdrawal of corticosteroids; the frequency is unknown.
Most modern steroid enemas are foam based - as the likelihood of someone with colitis being able to retain a water based enema is quite low. These act topically applying the steroid directly to the colon - with only small amounts being absorbed into the bloodstream. This makes side effects less likely. The downside is that they can only reach the descending colon and rectum - so for those with extensive colitis oral steroids may be needed. A combination of Entocort and steroid enemas can provide topical treatment to the majority of the colon - again minimizing side effects. As the two main steroid enemas differ quite greatly I will cover them separately.