For large cysts that don’t respond to other treatments, a drug called isotretinoin may be prescribed. This treatment reduces the size of the oil glands and is very effective, resulting in permanent improvement in about 85 percent of people with severe acne. However, it is also riskier because it can cause potentially severe side effects, including liver problems and severe depression . Due to the risk to the fetus, women must avoid becoming pregnant during and immediately after treatment. Therapy usually lasts 4-5 months. Patients should follow up regularly with their dermatologists during this time.
Moderation and regularity are good things, but not everyone can sleep eight hours, eat three good meals, and drink plenty of water a day. One can, however, still control acne despite one's frantic and unpredictable routine. Probably the most useful lifestyle changes one can make is to never to pick or squeeze pimples. Playing with or popping pimples, no matter how careful and clean one is, nearly always makes bumps stay redder and bumpier longer. People often refer to redness as "scarring," but fortunately, it usually isn't permanent. It's just a mark that takes months to fade if left entirely alone.